What Is Antiphospholipid Syndrome?
Antiphospholipid syndrome is an autoimmune condition that increases the risk of excessive blood clotting. The elevated risk is due to the presence of certain proteins (antiphospholipid autoantibodies) in the blood. Researchers believe the production of these autoantibodies may be triggered by an environmental factor, such as an infection, in an individual who has a genetic predisposition to developing the condition, which is often associated with connective tissue diseases such as systemic lupus erythematosus.
What Are the Effects of Antiphospholipid Syndrome?
Antiphospholipid autoantibodies may be present in the bloodstream for a long time without causing any excessive clotting. Most thrombotic events occur only if other conditions that increase the risk of blood clotting are present, such as prolonged inactivity. Other risk factors for thrombosis include hypertension, obesity, smoking and atherosclerosis.
Blood clots associated with antiphospholipid syndrome can occur anywhere within the circulatory system and can potentially affect any organ in the body. The resulting effects can vary depending on the location of a clot. For instance, blood clots in the arteries in the heart can lead to heart attacks, while blood clots in the arteries in the brain can lead to strokes. During pregnancy, the formation of blood clots in the placenta can lead to miscarriages.
Venous blood clots occur most frequently in the lower legs. These clots can potentially break away, travel to the lungs and cause a pulmonary embolism, a serious and possible life-threatening condition that can disrupt blood flow to the lung and reduce the amount of oxygen in the blood.
How Is Antiphospholipid Syndrome Treated?
In most cases, antiphospholipid autoantibodies are tested and detected only after a clotting event occurs. Therefore, the main goal of treatment is to prevent recurrences. Acute thrombotic events are usually treated with anticoagulants, initially with heparin and later with oral anticoagulants such as warfarin. In serious situations, a clot-dissolving medication may be given to break-down blood clots quickly.
Long-term oral anticoagulant therapy for antiphospholipid syndrome can affect a patient’s lifestyle, and the blood-thinning effects of the medication must be monitored by a physician on an ongoing basis. It is also important to manage the conventional risk factors for thrombosis, such as diabetes, high blood pressure, high cholesterol, obesity and smoking.
If you’d like to meet with a rheumatologist at Advanced Orthopaedics & Sports Medicine to explore your options for managing antiphospholipid syndrome, contact us to request an appointment at our state-of-the-art orthopedic institute in Houston, Texas.
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Everyone here is so professional and kind. Everything was explained to me so that could understand what had to be done. Haven’t had the surgery yet, will update when I have…. One month after surgery, started physical therapy and all is going well. Dr. Mack did such a great job. X Ray’s show the phenomenal work he did on my ankle. Thank you so much… The physical therapy here is great. They provide so much insight and help. Getting much better.
Excellent care and attention to patients. I recently had a total hip replacement and I am able to walk 6 weeks after surgery with no cane. Great feeling to be independant again. So happy to have such an excellent doctor, Dr.Thomas Tanous. His staff was excellent and encouraging as I healed from my surgery. I would definitely recommend Advanced Orthopaedics and Sports Medicine
Always awesome. Everyone is kind, very professional and thorough. Dr Blalock and his team go out of their way to help any way they can. Same with the group in OT. They work hard and are always helpful and pleasant. Recommend 100%
Advanced Orthopedics & Sports Medicine has, at 76, virtually given me a new lease on being mobile and active. I have seen Dr’s Tanous, Patel, and Cubbage for an assortment of neck, spine and hip problems. Steroid injections to spine by Dr. Patel and the bursa in my hips by Dr. Tanous have taken me from not being able to walk my dog to the end of the block without excruciating pain to walking her daily and even doing several 2 to 2.5 mile hikes on vacations in the last couple of years. I cannot praise them highly enough.
I highly recommend Advanced Orthopaedics and Sports Medicine whenever the need arises for great orthopaedic surgeons. They take care of you in a very professional and courteous manner. The Doctors do not rush out like most Doctors do, they sit down and explain what they find, what you need to do to get better and stay to find out if you have any questions or concerns. I also love the physical therapists that they have on premises if there is a need for physical therapy; you do not have to go anywhere else. The staff is also very professional and take care of your promptly. You do not have to wait a long time in the waiting room. All the Doctors are great but I appreciate very much Dr. Fehsenfeld, Dr. Mohr and Dr. Mills. I have peace of mind after I am being take care by these outstanding Doctors
I have found the staff to be courteous and professional. Lynn and Julie were wonderful to work with and took good care of me. And Dr. Brooks and Dr. Mack are excellent and I will seek their help with any and all Orthopedic issues involving my knees in the future.
Thanks for the help on strengthening my legs.after the back surgery, There was no pain shooting down the back of my legs after surgery. I am recovering well with no pain medications.after seven days. I sincerity appreciate Dr.Cubbage.expertise. He told me what to expect with the surgery and recovery. He was spot on and l feel lucky to get a great Doctor like Dr. Cubbage. I also want to thank his great staff for their professional assistance.
I highly recommend Advanced Orthopedic & Sports Medicine to anyone who needs anything dealing with bone replacement. They are THE BEST! Starting with the front office staff, all the techs, all the nurses and the anesthesiologists as well as the doctors are all supremely professional, kind, cordial, accommodating as well as being a Medical Community of their word! They are very concerned about your needs during and after your hospital stay.
They reach out to you afterwards to see how you are doing and I find that to be so hospitable in the culture and climate of our world today. Doctor. David Mack and his nurse Julie as well as the other staff are really the best and have a unique bedside as well as chair side manner. These are least to find qualities in healthcare today. Just to get someone to look at you while you explain as to why you are in for a visit today is a none find however; this staff is all of the above for mentioned and more! Please use this team for your Orthopedic needs and you will be happy with the outcome!